Tubule cytoskeleton organization, cell cycle unknown hydrolase activity, provisional unknown unknown

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Age-related DEGs involving three mo and 18 mo Wistar retinas Dio1 tsga10ip RGD1562234 Ugt2b1 Dio1 cytokine-mediated signaling pathway glutamate metabolic process regulation of transcription intermediate filament cytoskeleton response to hypoxia, regulation of blood pressure, regulation of apoptosis, regulation of I-kappaB kinase/Atractylodin chemical information NF-kappaB cascade intracellular signaling cascade, regulation of neuron apoptosis, regulation of RNA metabolic method 15,79 12,39 three,52 3,06 11,25 0,020378 0,021974 0,00011 0,036548 0,tsga10ip5,0,(A) Strain-related DeGs frequent for 3- and 18-mo-old comparisons among Wistar and oXYS retinas. Cerevisiae) Beta-1,4-N-acetyl-galactosaminyl transferase 3 piwi-like 2 (Drosophila) Interleukin 18 troponin t type 2 (cardiac) Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide Cadherin 19, type 2 prodynorphin Chloride intracellular channel 3 Laminin, 3 Ankyrin repeat and BtB (poZ) domain containing 2 DeNN/MADD domain containing 2C Similar to enolase S100 calcium binding protein A9 Myxovirus (influenza virus) resistance 2 Similar to guanylate binding protein family, member 6 Guanylate binding protein 5 Calcitonin-related polypeptide, Chemokine (C-X-C motif) ligand 2 Collagen, type III, 1 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial Collagen, type I, 1 Collagen, type I, 2 Deiodinase, iodothyronine, type I Growth differentiation factor 15 Solute carrier family 26, member 3 Insulin-like growth factor 2 binding protein 2 endothelin 2 Gene Symbol RGD1562234 Ugt2b1 Dio1 tsga10ip RGD1562234 Ugt2b1 Dio1 tsga10ip RGD1562234 Adh7 Cdh19 pdyn Clic3 Lamb3 Abtb2 Dennd2c F1ltp6_rat S100a9 Mx2 LoC685067 Gbp5 Calcb Cxcl2 Col3a1 Mthfd2 Gene ontology term negative PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/24247322 regulation of transcription cell surface receptor linked signal transduction MApKKK cascade, calcium-mediated signaling regulation of transcription lipid binding acetylgalactosaminyltransferase activity RNA processing, regulation of translation angiogenesis, response to hypoxia, immune response muscle tissue improvement FC four,04 three,31 3,1.Tubule cytoskeleton organization, cell cycle unknown hydrolase activity, provisional unknown unknown eye development, regulation of RNA, DNA metabolic approach heme biosynthetic course of action zinc ion binding generation of precursor metabolites and energy, hormone metabolic approach unknown unknown drug metabolic course of action FC -2,31 -2,25 -2,24 -2,05 -2,09 -2,03 -2,03 2,14 2,19 two,40 two,47 two,59 2,67 two,87 3,16 3,22 three,38 eight,44 13,78 20,12 22,04 30,87 35,16 up up p worth 0,000665 0,006756 0,000237 0,000805 0,016989 0,001796 0,001001 0,030785 0,006226 9,03e-08 0,00018 1.89e-05 0,02043 0,011592 0,008711 0,001306 0,03259 four,44e-09 1,11e-07 five,55e-08 5.54e-25 1.98e-66 0,003718 four,11e-28 0,B. Age-related DEGs involving three mo and 18 mo Wistar retinas Dio1 tsga10ip RGD1562234 Ugt2b1 Dio1 cytokine-mediated signaling pathway glutamate metabolic process regulation of transcription intermediate filament cytoskeleton response to hypoxia, regulation of blood pressure, regulation of apoptosis, regulation of I-kappaB kinase/NF-kappaB cascade intracellular signaling cascade, regulation of neuron apoptosis, regulation of RNA metabolic method 15,79 12,39 three,52 3,06 11,25 0,020378 0,021974 0,00011 0,036548 0,tsga10ip5,0,(A) Strain-related DeGs typical for 3- and 18-mo-old comparisons in between Wistar and oXYS retinas. Specified values of fold modify and adjusted p values refer for the 18 mo age. (B) Age-related DeGs in retina of 18 mo Wistar compared with 3-mo-old Wistar (FC cutoff PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/20954872 > 2.0 and adjusted p values 2.0 and adjusted p values